Pancreatic Cancer
Conditions
Keywords
pancreaticoduodenectomy, reconstruction
Brief summary
One of the most common complications of pancreaticoduodenectomy (PD) is delayed gastric emptying (DGE), otherwise known as gastroparesis, which is not fatal but results in prolonged hospital stay and increased hospital costs. Delayed gastric emptying is defined as nasogastric decompression after postoperative day (POD) 10 or a failure to tolerate a regular diet after POD 14. The incidence of DGE has been reported to range from 5% to 72%.
Detailed description
We hypothesized that the hand-sewn, two-layered, or continuous suture, could induce anastomotic edema to indeed the afferent peristalsis, which is one of the causes of DGE.
Interventions
PROCEDURER-Y reconstruction
The reconstruction was performed by R-Y anastomosis.
Sponsors
Kochi University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* These patients were to undergo elective pancreatic head resection for the treatment of periampullary mass
Exclusion criteria
* A body weight loss greater than 10% during the six months prior to surgery * The presence of distant metastases * Seriously impaired function of vital organs due to respiratory, renal or heart disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of DGE | 3-6 months |
Secondary
| Measure | Time frame |
|---|---|
| the incidence of other complication associated with reconstruction | 3-6 months |
Countries
Japan
Contacts
Primary ContactTakehiro Okabayashi, MD, PhD
Backup ContactKazuhiro Hanazaki, Prof
Outcome results
None listed