Predictors of Anticoagulation Control on Warfarin Therapy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00905177

Enrollment

687

Registered

2009-05-20

Start date

2009-06-30

Completion date

2013-08-31

Last updated

2016-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation, Deep Vein Thrombosis, Heart Valve Replacement

Keywords

Atrial Fibrillation, deep vein thrombosis, anticoagulation, warfarin, coumadin

Brief summary

The goal of this research study is to develop better dosing of anticoagulation medication in both Caucasian and African Americans through analysis of various genetic factors.

Detailed description

This is a prospective cohort study among adult patients requiring warfarin therapy. Patients presenting for anticoagulation will be identified at the start of therapy and followed throughout their course until they reach maintenance dose. We will then develop a dosing equation for warfarin using patient, environmental and genetic factors.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to No maximum

Healthy volunteers

Inclusion criteria

* All Caucasians and African Americans who are new to warfarin therapy

Exclusion criteria

* Under 21 years of age * Non caucasian * Non african american * Have an abnormal INR before warfarin or heparin therapy * Unable to provide consent

Countries

United States

Outcome results