Effects of Physical Training on Heart Rate Variability and Exercise Capacity in Diabetes With Autonomic Neuropathy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00904761

Enrollment

Unknown

Registered

2009-05-20

Start date

2001-10-31

Completion date

2002-05-31

Last updated

2012-12-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus

Keywords

diabetes mellitus, autonomic neuropathy, exercise training, exercise capacity, heart rate variability

Brief summary

This study aimed to investigate effects of physical training on exercise capacity and changes of heart rate variability (HRV) at rest, during exercise, and post-exercise in the patient with diabetes with autonomic neuropathy (DAN).

Interventions

OTHERexercise training

The exercise group took supervised aerobic training twice per week at hospital and thrice per week at home for eight weeks at the intensity of 60-70% VO2peak

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 65 Years

Healthy volunteers

Inclusion criteria

* aged under 65 years old * receiving regular treatment * HbA1c \< 8.0 * decreased HR response in deep breathing maneuver

Exclusion criteria

* heart disease * neuro-musculo-skeletal diseases * taking any medication that may affect HRV (such as α or β-blockers)

Design outcomes

Primary

Measure	Time frame
heart rate variability	8 weeks
exercise capacity	8 weeks

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026