Cervical Cancer
Conditions
Keywords
DNA cytometry, Cytology, Diagnosis accuracy
Brief summary
Very few screenings of any kind will be possible during a woman's lifetime in most low-resource regions, where 80% of the half-million global cases of cervical cancer occur every year. Although a single round of human papillomavirus (HPV) testing was associated with a significant decline in the rate of advanced cervical cancers and associated deaths, whether other methods like as DNA image cytometry can be used as an more accurate means than others in screening cervical cancer or not is yet to be verified. In addition, the accuracy of both DNA image cytometry and conventional cytology is not well known. The investigators hypothesized that DNA image cytometry was superior in screening cervical cancer than conventional cytology.
Interventions
None listed
Sponsors
Nanjing Medical University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Currently or had been married * Not pregnant * Had an intact uterus with no prolapse * Had no history of cervical cancer * Living in China
Exclusion criteria
* Not willing to participate or finish the study at any time * History of cervical surgeries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of cervical cancer. | From the testing performed by the investigator (0h) to one year follow-up period |
Secondary
| Measure | Time frame |
|---|---|
| The rate of death. | One year follow-up period after screening. |
| The incidence of cervical intraepithelial neoplasia. | From the screening (0h) to one year follow-up period |
| Cervical inflammation | From the screening (0h) to one year follow-up period |
Countries
China
Outcome results
None listed