Lebanese Interhospital Pneumococcal Surveillance Program

Lebanese Interhospital Pneumococcal Surveillance Program (LIPSP)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00901602

Acronym

LIPSP

Enrollment

700

Registered

2009-05-14

Start date

2005-10-31

Completion date

2030-10-31

Last updated

2023-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacteremia, Meningitis, Pneumonia, Sepsis

Keywords

streptococcus pneumoniae, pneumococcus, pneumonia, meningitis, serotypes, bacteremia, sepsis

Brief summary

Streptococcus pneumoniae (pneumococcus) is a bacterium that causes severe infections in children and adults such as meningitis, pneumonia, and blood stream infection. There are many types of these bacteria defined by the type of sugar coat that they have. These are classified as serotypes. There are common serotypes that cause severe disease and are preventable by vaccination of children. Other less common types are more difficult to prevent. The investigators aim to determine the serotypes that cause invasive pneumococcal disease in Lebanon and to study their sensitivity to different antibiotics. The investigators will collect bacterial isolates from different hospitals in Lebanon isolated from the blood or spinal fluid of patients with invasive pneumococcal disease. This information will help the investigators determine the usefulness of available pneumococcal vaccines in preventing these infections. The data will be distributed to all primary care physicians treating children in Lebanon and will be shared with the Ministry of Health.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Days to No maximum

Healthy volunteers

Inclusion criteria

* Samples included in the study are those that are: * culture proven * invasive pneumococcal infections * in patients of all ages admitted to different hospitals all over Lebanon * Acceptable samples include: * positive isolates from blood * cerebrospinal fluid * other normally sterile body sites such as empyema fluid, abscesses, joint fluid, middle ear fluid obtained by tympanocentesis in the operating room, and lung needle aspiration

Exclusion criteria

* non S. pneumoniae isolates

Design outcomes

Primary

Measure	Time frame
Serotype prevalence of S. pneumoniae in invasive pneumococcal disease	yearly

Secondary

Measure	Time frame
Determine the antibiotic sensitivity of S. pneumoniae and the association with specific serotypes	yearly

Countries

Lebanon

Contacts

Primary ContactGhassan S Dbaibo, M.D.

gdbaibo@aub.edu.lb+961-1-749235

Backup ContactMireille Lteif, RN

ml12@aub.edu.lb+961-1-350000

Outcome results