SWOG-9245 Collecting and Storing Tissue Samples From Patients With Relapsed or Recurrent Non-Hodgkin Lymphoma After Treatment on a Southwest Oncology Group Clinical Trial

Central Lymphoma Repository Tissue Procurement Protocol for Relapse or Recurrent Disease

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00898872

Enrollment

Registered

2009-05-12

Start date

1993-03-31

Completion date

2011-07-31

Last updated

2013-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lymphoma

Keywords

recurrent grade 3 follicular lymphoma, recurrent adult diffuse small cleaved cell lymphoma, recurrent adult diffuse mixed cell lymphoma, recurrent adult diffuse large cell lymphoma, recurrent adult immunoblastic large cell lymphoma, recurrent adult lymphoblastic lymphoma, recurrent adult Burkitt lymphoma, recurrent adult grade III lymphomatoid granulomatosis, recurrent grade 1 follicular lymphoma, recurrent grade 2 follicular lymphoma, recurrent mantle cell lymphoma, recurrent marginal zone lymphoma, recurrent small lymphocytic lymphoma, extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue, nodal marginal zone B-cell lymphoma, splenic marginal zone lymphoma, Waldenström macroglobulinemia, adult nasal type extranodal NK/T-cell lymphoma, recurrent childhood grade III lymphomatoid granulomatosis, recurrent childhood large cell lymphoma, recurrent childhood lymphoblastic lymphoma, recurrent childhood small noncleaved cell lymphoma, childhood diffuse large cell lymphoma, childhood immunoblastic large cell lymphoma, childhood Burkitt lymphoma, childhood nasal type extranodal NK/T-cell lymphoma

Brief summary

RATIONALE: Collecting and storing samples of tissue from patients with non-Hodgkin lymphoma to study in the laboratory may help the study of cancer in the future. PURPOSE: This laboratory study is collecting and storing tissue samples from patients with relapsed or recurrent non-Hodgkin lymphoma after treatment on a Southwest Oncology Group (SWOG) clinical trial.

Detailed description

OBJECTIVES: * Acquire fresh snap-frozen lymphoma tissue from patients with relapsed or recurrent non-Hodgkin lymphoma after treatment on a Southwest Oncology Group (SWOG) clinical trial. * Establish a standard set of procedures for routine acquisition, banking, and study of lymphoma tissues within the SWOG. * Use repository tissue to establish clinical correlations via presently activated phenotyping studies and future projected molecular studies assessing specimen DNA and RNA status. * Examine the biology of therapy failure in relationship to changes in pretreatment and post-treatment immunophenotypic data. OUTLINE: This is a multicenter study. Tissues collected at biopsy are snap-frozen and archived for future molecular and genetic studies. PROJECTED ACCRUAL: Not specified

Interventions

OTHERcryopreservation

Study design

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

DISEASE CHARACTERISTICS: * Diagnosis of relapsed or recurrent non-Hodgkin lymphoma (NHL) * Previously registered on 1 of the following SWOG clinical trials for previously untreated NHL: * SWOG-8410 * SWOG-8503 * SWOG-8508 * SWOG-8516 * SWOG-8736 * SWOG-8809 * SWOG-8907 * SWOG-8954 * SWOG-9125 * SWOG-9240 * SWOG-9320 * SWOG-9349 * SWOG-9432 * SWOG-9501 * SWOG-9703 * SWOG-S9704 * SWOG-9800 * Tissue samples of relapsed or recurrent disease available PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * See Disease Characteristics

Design outcomes

Primary

Measure	Time frame
Acquisition of snap-frozen lymphoma tissues	July 2011

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026