Hypertension, Myoma
Conditions
Keywords
myoma, hypertension, erythropoetin, blood pressure, erythropoetin level
Brief summary
The effect of myoma removal was studied on 28 patients with hypertension and myoma by holter monitoring and erythropoetin level check.
Detailed description
Background: Myoma is the most common gynecoid tumor and produces many vasoactive substances, which may be a cause for secondary hypertension. Early reports suggested the association of myoma and hypertension. We studied the effect of myoma removal on hypertension and erythropoietin level to evaluate this hypothesis. Patients & Methods: In this single centered prospective cohort study, in twenty eight patients who were candidates for myomectomy due to myoma, 24 hour holter monitoring of blood pressure and serum erythropoietin were checked before and 6 weeks after hysterectomy.
Interventions
PROCEDUREmyoma removal
surgical removal of myoma by hysterectomy
Sponsors
Shiraz University of Medical Sciences
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
22 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* candidate for myoma removal by hysterectomy * operable * hysterectomy is indicated
Exclusion criteria
* patient refusal * inoperable patients * other secondary cases of hypertension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24 hour holter monitoring of blood pressure | 6 weeks |
Secondary
| Measure | Time frame |
|---|---|
| erythropoetin level | 6 weeks |
Countries
Iran
Outcome results
None listed