Bone Marrow and Blood Samples From Patients With Metastatic Choroid Melanoma

Evaluation of the Detection of Tumor Cells in Bone Marrow and Blood in Patients With Choroid Melanoma

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00897624

Enrollment

Registered

2009-05-12

Start date

2007-11-30

Completion date

Unknown

Last updated

2011-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraocular Melanoma

Keywords

metastatic intraocular melanoma, ciliary body and choroid melanoma, medium/large size, ciliary body and choroid melanoma, small size

Brief summary

RATIONALE: Studying samples of bone marrow and blood from patients with cancer may help doctors find out the extent of disease. PURPOSE: This research study is collecting bone marrow and blood samples from patients with metastatic choroid melanoma.

Detailed description

OBJECTIVES: Primary * Develop and validate a method of detecting tumor cells in the bone marrow and blood in patients with metastatic choroid melanoma. OUTLINE: While patients are under general anesthesia for standard treatment of their disease, samples of bone marrow from the iliac crest and blood are collected. Samples are analyzed for the expression of tyrosinase and Melan-a via RT-PCR.

Interventions

GENETICgene expression analysis

GENETICreverse transcriptase-polymerase chain reaction

OTHERlaboratory biomarker analysis

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

DISEASE CHARACTERISTICS: * Choroid melanoma * Metastatic disease * Planning to undergo general anesthesia PATIENT CHARACTERISTICS: * Not pregnant or nursing * No contraindications to the collection of a bone marrow sample * No patient deprived of liberty or under trusteeship (including guardianship) * No social or psychological situations that preclude the ability to give consent PRIOR CONCURRENT THERAPY: * Not specified

Design outcomes

Primary

Measure	Time frame
Detection of micro-metastatic cells in 20 x 10^6 nucleated cells	—

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026