Calculus
Conditions
Keywords
Melamine, Calculus, Kidney, Child
Brief summary
The purpose of this study is to investigate the lesions, clinical features and outcome in young children with melamine-related-calculus.
Detailed description
1. To investigate the outcome of melamine-related-calculus. * The change of calculus. * The change of obstruction features,including hydronephrosis and ureterectasia. * The change of the urinalysis. 2. To investigate the change of renal function in children with melamine-related-calculus during the follow up. * Creatinine, urea and uric acid. * α and β2 microglobulin. 3. To analysis the factors might be associated with the outcome. * The characteristics of patients: age, gender, and so on. * The characteristics of calculus: location, size, and so on.
Interventions
None listed
Sponsors
Zhejiang University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 5 Years
Healthy volunteers
Yes
Inclusion criteria
* children with melamine-related-calculus: with a history of melamine contaminated products * the parents leave the detailed information for contact and willing to be recalled
Exclusion criteria
* children with other congenital renal abnormality * children with hypercalciuria * children have abnormality of parathyroid gland
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The calculus measured by sonography | at 1, 3, 6 and 12 months |
Secondary
| Measure | Time frame |
|---|---|
| Renal function (e.g., creatinine, microglobulin) | at 1, 3, 6 and 12 months |
Countries
China
Outcome results
None listed