Characterisation of Fractionated Electrograms Critical for Maintenance of Atrial Fibrillation (AF)

Characterisation of Fractionated Electrograms Critical for Maintenance of AF

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00894400

Acronym

CAFE AF

Enrollment

Registered

2009-05-07

Start date

2009-04-30

Completion date

2011-05-31

Last updated

2011-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Keywords

AF, catheter ablation, fractionated electrogram, complex fractionated atrial electrogram (CFAE)

Brief summary

The purpose of this study is to characterise which fractionated electrogram morphologies are important to target in the catheter ablation of atrial fibrillation.

Interventions

PROCEDUREcatheter ablation

catheter ablation using radiofrequency energy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients with persistent AF listed for first time catheter ablation

Exclusion criteria

* age \< 18 years * pregnancy * contraindications to procedure * recent myocardial infarction, coronary intervention, or cardiac surgery

Design outcomes

Primary

Measure	Time frame
change in AF cycle length when targeting fractionated electrograms of different morphology.	immediate

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 28, 2026