The Effect of Sildenafil on Sleep-Disordered Breathing in Obese Patients With Sexual Dysfunction

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00893191

Enrollment

Registered

2009-05-05

Start date

2009-05-31

Completion date

Unknown

Last updated

2009-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Sexual Dysfunction, Sildenafil, Sleep Apnea

Brief summary

Sildenafil has been shown to aggravate sleep-disordered breathing in patients with severe obstructive sleep apnea. The aim of the present study is to examine the frequency of sleep-disordered breathing in obese patients who are candidates for treatment with sildenafil for sexual dysfunction. In addition we wish to assess the effect of sildenafil on sleep-disordered breathing.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

MALE

Age

40 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Age - 40-65 years * BMI equal to or over 30

Exclusion criteria

* A known cardiorespiratory, liver or kidney disease * Treatment with nitrates or alfa blockers * Performed polysomnography in the past

Design outcomes

Primary

Measure	Time frame
apnea hypopnea index after sildenafil vs. placebo	Hours

Secondary

Measure	Time frame
Sleep parameters (latency, efficiency etc) following sildenafil vs. placebo	hours

Countries

Israel

Contacts

Primary ContactIsaac Shpiree, MD

I_shpirer@yahoo.com972-8-9779024

Backup ContactArnon Elizur, MD

elizura@gmail.com972-8-9779817

Outcome results