Molecular Markers in Cervical Cancer Screening in the Feasibility of the Mathematical Markov Model Analysis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00889902

Enrollment

200

Registered

2009-04-29

Start date

2009-04-30

Completion date

2011-07-31

Last updated

2009-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Cancer

Keywords

Molecular Markers, Cervical Cancer, Screening, Makov

Brief summary

The purpose of this study is to: 1. make p16INK4A as a cervical cancer screening of tumor markers, cytology improve existing diagnostic sensitivity, specificity, repeatability and validity, so as to effectively prompted the early discovery and diagnosis of cervical cancer. 2. reduce screening costs, screening and benefits into quantitative evaluation, for our country to develop cervical cancer prevention and control strategy to provide a reliable theoretical basis.

Detailed description

1. To carry out large-scale prospective randomized controlled clinical study to evaluate the cytological molecular markers Detect + P16INK4A methods of screening accuracy and reliability, as well as the screening method of the biological effects. 2. Markov set up mathematical model of screening tests to quantify the inputs and the evaluation proceeds. With a view to optimize and perfect a simple, convenient, practical and efficient program of cervical cancer screening.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

25 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Married women aged 25 to 65-year-old with risk factors * No tumor and pelvic radiation therapy history * Non-pregnant women at present

Countries

China

Contacts

Primary ContactHong B Cai, Doctor

Chb2105@163.com0086-027-67813044

Backup ContactYing J Huang

Outcome results