The Role of High Resolution-Computed Tomography (CT) in Tuberculosis (TB) Outbreak Investigation

The Role of Addition of High Resolution-CT in Outbreak Investigation of Tuberculosis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00889759

Enrollment

Registered

2009-04-29

Start date

2007-12-31

Completion date

2009-04-30

Last updated

2009-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tuberculosis

Keywords

Tuberculosis, Outbreaks

Brief summary

The aim of this study is to evaluate the role of high-resolution computed tomography of the chest (HRCT) in the investigation of an outbreak of TB that developed in the South Korean army.

Detailed description

Outbreak investigation including tuberculin skin test (TST), QuantiFERON® TB Gold In-Tube (QFT), and simple chest radiography (CXR) will be performed. For participants with any abnormal findings in these tests, HRCT will be carried out. Active pulmonary TB is diagnosed based on sputum studies or HRCT findings. In addition, participants with positive results both in TST and QTF will be treated as having a latent TB infection (LTBI). TST and QTF were repeated in participants with positive result in one of these tests. CXR will be repeated in all participants at 3 and 6 months of follow-up.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

MALE

Healthy volunteers

Yes

Inclusion criteria

* All soldiers who assigned to the military battery where a tuberculosis outbreak occurred

Exclusion criteria

* Soldiers who could not complete study

Outcome results