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Deep Anterior Lamellar Keratoplasty (DALK)

Deep Anterior Lamellar Keratoplasty by Big-Bubble Technique: Results and Complications

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00887900
Acronym
DALK
Enrollment
40
Registered
2009-04-24
Start date
2006-01-31
Completion date
2008-12-31
Last updated
2009-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Keratoconus

Keywords

lamellar keratoplasty, keratoconus, penetrated keratoplasty, Visual acuity

Brief summary

The purpose of this study is to report outcomes of deep anterior lamellar keratoplasty (DALK) using the big-bubble technique.

Detailed description

Purpose: To report outcomes of deep anterior lamellar keratoplasty (DALK) using the big-bubble technique. Methods: Thirty four unselected consecutive patients were submitted to DALK big-bubble technique. Intraoperative and postoperative complications, postoperative uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), spherical equivalent (SE), corneal topography, and endothelial cell density were evaluated. All patients were followed for at least 6 months.

Interventions

PROCEDUREDeep anterior lamellar keratoplasty (DALK)

Deep anterior lamellar keratoplasty (DALK) using the big-bubble technique.

PROCEDUREPenetrated keratoplasty

Regular corneal transplant using the penetrated keratoplasty technique

Sponsors

Hospital Oftalmologico de Brasilia
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* keratoconus

Exclusion criteria

* central endothelial cell count less than 2000 cells/mm2 * glaucoma or intraocular pressure greater than 21 mmHg * amblyopia * retinal abnormalities * diabetes mellitus * steroid or immunosuppressive treatment * connective tissue diseases

Design outcomes

Primary

MeasureTime frame
To report outcomes of deep anterior lamellar keratoplasty (DALK) using the big-bubble technique.12 months

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 27, 2026