Diabetes Mellitus, Type 2, Exercise, Treatment
Conditions
Keywords
Diabetes mellitus, Exercise, Endurance, Resistance, Continuous glucose monitoring system
Brief summary
Many studies were already performed showing beneficial cardiovascular and metabolic effects of physical training for type 2 diabetic patients. However, glucose profile during and immediately after a short period of aerobic and/or resistance training was not studied yet. Continuous glucose monitoring system (CGMS) has now been added to the repertoire of technological devices useful in the management of patients with diabetes. Such monitoring enables clinicians to detect occult hypoglycemia and hyperglycemia not otherwise discernable with intermittent testing of blood glucose. The main aim of the present study is to investigate continuous blood glucose profile (using CGMS) over 72h, beginning 24h before and ending 24h after a single bout of aerobic or aerobic/resistance physical training in type 2 diabetic patients.
Detailed description
Many studies were already performed showing beneficial cardiovascular and metabolic effects of physical training for type 2 diabetic patients. However, glucose profile during and immediately after a short period of aerobic and/or resistance training was not studied yet. Continuous glucose monitoring system (CGMS) has now been added to the repertoire of technological devices useful in the management of patients with diabetes. Such monitoring enables clinicians to detect occult hypoglycemia and hyperglycemia not otherwise discernable with intermittent testing of blood glucose. The main aim of the present study is to investigate continuous blood glucose profile (using CGMS) over 72h, beginning 24h before and ending 24h after a single bout of aerobic or aerobic/resistance physical training in type 2 diabetic patients.
Interventions
BEHAVIORALAcute aerobic exercise
Aerobic exercise (on a cycle ergometer, for 50 min)
BEHAVIORALAcute aerobic-resistance exercise
Aerobic-resistance exercise (on a cycle ergometer plus strength training, for 50 min in total)
Sponsors
Hospital de Clinicas de Porto Alegre
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
35 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Type 2 diabetic patients treated with diet and metformin, 35-65 years old
Exclusion criteria
* Type 1 diabetic patients * Treatment with insulin or sulphonylureas or glitazones * Proliferative retinopathy * Severe autonomic neuropathy * Coronary artery disease * Baseline fasting plasma glucose\>200 mg/dl * Peripheral artery disease * Amputation * Heart failure * Diabetic nephropathy * Renal failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of the prevalence of hyperglycemic peaks during a 24-h period after a bout of aerobic or aerobic/resistance exercise in type 2 diabetes patients on metformin/diet therapy. | 24h |
Countries
Brazil
Outcome results
None listed