A Randomized Controlled Trial Comparing Two Timing Regimens of Pico-salax for Colon Cleansing Prior to Colonoscopy

A Randomized Controlled Trial Comparing Two Timing Regimens of Pico-salax for Colon Cleansing Prior to Colonoscopy.

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00885274

Enrollment

250

Registered

2009-04-21

Start date

2008-11-30

Completion date

2011-08-31

Last updated

2015-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colonoscopy

Brief summary

Pico-Salax is an osmotic and stimulant bowel cleansing agent used prior to colonoscopy. It is unknown whether splitting the doses (i.e. taking the second dose the morning of the colonoscopy) results in a better bowel cleansing, as research with other agents suggests this may be the case. This study aims to assess whether splitting the dose of Pico-Salax results in a better bowel cleansing than traditional dosing.

Interventions

DRUGPico-Salax

Both doses of Pico-Salax taken the evening prior to colonoscopy

DRUGSplit Dose Pico-Salax

One dose of Pico-Salax taken the evening prior to colonoscopy and the other the morning of the procedure.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* colonoscopy indicated

Exclusion criteria

* congestive heart failure * ascites * renal failure * hyponatremia * previous intestinal surgery

Design outcomes

Primary

Measure	Time frame
bowel cleansing assessed by the Ottawa Bowel Preparation Scale	day of colonoscopy

Secondary

Measure	Time frame
patient tolerance of preparation	day of colonoscopy

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 27, 2026