Aortic Valve Disease, Cerebral Stroke
Conditions
Brief summary
The purpose of this study is to compare the incidence of silent and apparent cerebral embolism between conventional and minimal-invasive transfemoral aortic valve repair.
Detailed description
Patients undergoing aortic valve repair (AVR) are included prospectively into the study. AVR techniques include the conventional technique, the transfemoral and the transapical approach. Before the intervention CT of the chest is performed preoperatively to assess the degree of aortic and aortic valve calcification. Patients undergo MRI of the brain, including diffusion weighted imaging (DWI) and neurological assessment (NIHSS score) within 48 h before and after the procedure to assess occurrence of cerebral embolism.
Interventions
None listed
Sponsors
Study design
Eligibility
Inclusion criteria
* aortic valve replacement
Exclusion criteria
* contraindication to undergo MRI
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Silent cerebral embolism | 48 hours |
Secondary
| Measure | Time frame |
|---|---|
| Apparent cerebral embolism | 48 hours |
Countries
Germany