Skip to content

Mindfulness Based Stress Reduction for Posttraumatic Stress Disorder: A Pilot Study

Mindfulness-Based Stress Reduction for Posttraumatic Stress Disorder: A Pilot Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00880152
Acronym
MBSRforPTSD
Enrollment
50
Registered
2009-04-13
Start date
2008-09-30
Completion date
2009-12-31
Last updated
2010-09-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Stress Disorders, Post-Traumatic

Keywords

stress, mindfulness, trauma

Brief summary

PTSD is a common consequence of war, for soldiers and civilians. PTSD results in hyperarousal, avoidance, numbing, and re-experiencing, causing persistent decreased quality of life. Mindfulness involves the ability to bring attention to the present moment without judgment; this ability is correlated with measures of mental health. Within health care, mindfulness is taught as an 8-week course called Mindfulness-Based Stress Reduction (MBSR). MBSR is unstudied for PTSD. We propose to assess the feasibility of MBSR as an intervention for PTSD, since it may affect hypervigilance, avoidance, and reactivity associated with this disorder. Specific Aims: Aim 1: Assess the feasibility of recruiting and retaining a sample of veterans with PTSD to complete a study protocol that involves randomization to usual care or usual care plus MBSR. Aim 2: Apply measures of PTSD symptom severity, depression and quality of life before and after randomization, to assess whether there is evidence of benefit and whether MBSR warrants further study for PTSD, and allow calculation of standardized effect sizes. Aim 3: Apply a validated measure of mindfulness before and after treatment. Aim 4: Explore the relationship between PTSD symptoms, mindfulness score, and frequency of meditation practice.

Interventions

BEHAVIORALMindfulness-based stress reduction

An 8-week course in mindfulness training

Sponsors

Puget Sound Partners for Global Health
CollaboratorUNKNOWN
Seattle Institute for Biomedical and Clinical Research
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Must have PTSD

Exclusion criteria

* Active substance use * Active suicidal ideations * Borderline or antisocial personality disorder

Design outcomes

Primary

MeasureTime frame
PTSD symptom scorebaseline, after MBSR and 4 months later

Secondary

MeasureTime frame
depression (PHQ9)baseline, after MBSR and 4 months later

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026