Influence of Corticoids on Renal Function in Cardiac Surgery

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00879931

Enrollment

Registered

2009-04-13

Start date

2013-01-31

Completion date

2015-07-31

Last updated

2022-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective Cardiac Surgery

Brief summary

Hypothesis: Corticoid treatment in cardiac surgery works renal protective. Study design: Randomized, double blind trial in which one group of patients will receive methylprednisolone and the other group (control) will receive placebo NaCl 0.9%.

Interventions

DRUGMethylprednisolone

Methylprednisolone

DRUGPlacebo

Placebo (NaCl 0.9%)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Inclusion criteria

* age between 20-80 year * patients scheduled for elective cardiac surgery. * preoperative creatinine levels of \< 2mg/dl * no corticoid treatment

Exclusion criteria

* non-elective surgery * patiënts with renal dysfunction: creatinine \> 2mg/dl * patiënts treated with corticoids

Design outcomes

Primary

Measure	Time frame
Renal dysfunction and renal failure postoperatively in cardiac surgery	within 48 hours after cardiac surgery

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026