Prize Reinforcement Contingency Management for Cocaine Dependence: a 24-week Randomized Controlled Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00877435

Enrollment

Registered

2009-04-07

Start date

2008-09-30

Completion date

2014-10-31

Last updated

2015-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cocaine-related Disorders

Brief summary

The purpose of this study is to determine whether prize-based contingency management (prizeCM) combined with cognitive behavioral therapy (CBT) is more effective in the treatment of of cocaine-dependent patients compared to CBT only. Patients were randomized to prizeCM + CBT (experimental group) or to CBT (control group) an treated over 24 weeks. It is the first trial of this type in Europe.

Interventions

BEHAVIORALCognitive behavioral therapy (CBT)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* cocaine dependence, aged 18 or older, other dependences

Exclusion criteria

* severe somatic, brain, or psychiatric disease, attention deficit disorders with medication methylphenidate

Design outcomes

Primary

Measure	Time frame	Description
retention in treatment, cocaine abstinence	24 weeks	cocaine abstinence: at least 3 consecutive weeks of cocaine abstinence, the maximum number of weeks of continous abstinence and proportions of cocaine-free urine samples during the entire 24-week and at 6-month follow-up.

Secondary

Measure	Time frame	Description
patients' satisfaction with the therapy, clinical measures	24 weeks	patients' satisfaction with prize-based contingency management and with CBT

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026