Chronic Bronchitis, Disease Exacerbation
Conditions
Keywords
Acute Exacerbations of Chronic Bronchitis, Avelox, Bronchitis
Brief summary
This study is a local, prospective, open-label, company-sponsored, non interventional, multi-center study. Patients documented must suffer from an acute exacerbation of chronic bronchitis and take at least one dose of Moxifloxacin injection.The primary objective is to obtain clinical effectiveness and safety data of Moxifloxacin injection in the treatment of acute exacerbations of chronic bronchitis in patients in whom Moxifloxacin was routinely prescribed. The secondary objective is to find out the possible correlation between the risk factors (sex, smoking, number of previous exacerbations, etc) and AECB, the different treatment effectiveness according to Anthonisen classification. This study will also collect the data of pathogens by sputum culture and the defervescence time of Moxifloxacin injection in treating Acute Exacerbations of Chronic Bronchitis (AECB).
Interventions
Patients from the normal praxis routine, treated with Moxifloxacin injection with/without sequential tablet treatment according to the local product information
Sponsors
Bayer
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients at least 18 years of age with a diagnosis of AECB treated with Moxifloxacin injection with/without sequential tablet treatment
Exclusion criteria
*
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical cure rate:clinical cure was defined as disappearance of acute signs and symptoms | up to 21 days |
Secondary
| Measure | Time frame |
|---|---|
| Time to cure: time when symptoms are disappeared after Moxifloxacin treatment | up to 21 days |
| Improvement time: time when patients feel improvemen | up to 21 days |
| Time of patients recover from fever | up to 21 days |
| Clinical efficacy rate of Moxifloxacin | up to 21 days |
Countries
China
Outcome results
None listed