Acute Respiratory Failure
Conditions
Keywords
CPAP, Acute Respiratory Failure
Brief summary
The aim of this study is to evaluate the performance, the tolerability and the efficacy on gas-exchange of different CPAP (Continuous Positive Airway Pressure) systems.
Detailed description
Three CPAP systems are studied for each patient at the same level of PEEP: 1) continuous high-flow CPAP with fixed value PEEP valve; 2) continuous high-flow CPAP with Boussignac PEEP valve; 3) demand flow CPAP, supplied by a ventilator.
Interventions
PROCEDURECPAP system
Evaluating the effects of different CPAP systems on respiratory mechanics, respiratory effort and gas-exchange CPAP systems: Continuous high-flow CPAP with fixed value PEEP valve Continuous high-flow CPAP with Boussignac valve Demand flow CPAP supplied by ventilator
Sponsors
Policlinico Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Intubated-tracheostomized subjects receiving CPAP during the weaning from invasive mechanical ventilation
Exclusion criteria
* Hemodynamic instability * Barotrauma * Severe myopathy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Respiratory mechanics, work of breathing, end-expiratory lung volume (EELV) and gas exchange | 30 minutes |
Secondary
| Measure | Time frame |
|---|---|
| Comfort of breathing | 30 minutes |
Countries
Italy
Outcome results
None listed