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Evaluation of Inspiratory Muscle Strength Early After Coronary Artery Bypass

Inspiratory Muscle Strength as a Determinant of Functional Capacity Early After Coronary Artery Bypass Graft Surgery

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00873028
Enrollment
20
Registered
2009-04-01
Start date
2004-08-31
Completion date
2006-01-31
Last updated
2009-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

Physical therapy, Inspiratory muscles, Exercise

Brief summary

The purpose of this study is to evaluate the effects of a 6-day postoperative in hospital cardiopulmonary rehabilitation program on inspiratory muscle strength and its potential association with improved functional capacity after coronary artery bypass grafting surgery.

Detailed description

Eligible patients were randomized to a cardiopulmonary rehabilitation program (Rehab; n = 10) or to usual care (Control; n = 10). The randomization was done by the Graphpad StatMate computerized program. Those patients assigned to Control were followed by their own physicians, received routine nursing assistance, were visited daily by the one of the investigators (CPM), but were not exposed to any specific respiratory or motor physical intervention. Those randomized to Rehab received the same medical and nursing care, but followed a structured physical therapy program twice a day.

Interventions

OTHERIn Hospital Cardiopulmonary Rehabilitation

The program consisted of bronchial hygiene characterized by detachment and removal of secretions and respiratory exercises which were applied in the respiratory muscles in order to strengthen and increase the resistance. Patients were instructed to maintain diaphragmatic breathing, at a rate of 12 to 18 breaths per minute during EPAP mask use, and the expiratory pressure was increased progressively in the following fashion: 3-8 cm H2O during 3-12 minutes. Also, they performed flexion/extension of hip and knee, active free exercises for upper limbs, ambulation exercise and ascent/descend of stairs

Sponsors

Hospital de Clinicas de Porto Alegre
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
ALL
Age
21 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* Previous history of more than one vessel coronary artery disease * Lifelong abstinence from tobacco * Formal indication for CABG

Exclusion criteria

* Patients older than 75 years of age * Chronic renal failure (dialysis for more than 3 months) * Unstable angina in the 48 hours prior to CABG * Moderate or severe valve disease * Complex cardiac arrhythmia's * Stroke * Inability to exercise the lower limbs * Previous pulmonary disease (forced vital capacity \[FVC\] \< 80% of predicted and/or forced expiratory volume in 1 s \[FEV1\] \< 70% of predicted) * Previous history of asthma.

Design outcomes

Primary

MeasureTime frame
Maximal inspiratory and expiratory pressure were measured (before, 7 and 30 days after surgery).From 1 day before surgery up to 30 days after surgery (CABG)

Secondary

MeasureTime frame
Six-minute walk test (6MWT) was performed 7 days after surgery, and maximal cardiopulmonary exercise testing (CPET) was performed 30 days after CABG.From 7 days after surgery up to 30 days after surgery (CABG)

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026