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Risk Factors for Postpartum Psychosis

Potential Risk Factors for Postpartum Psychosis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00872313
Acronym
RIFPP
Enrollment
4000
Registered
2009-03-31
Start date
2009-02-28
Completion date
2012-08-31
Last updated
2014-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum Period, Psychosis

Keywords

Labor, Psychology, Postpartum Psychology

Brief summary

A range of psychological disorders occur in women in the postpartum period. These include the blues, which occurs in the first days after birth and which is very common and self-limiting; severe psychoses often associated with mania or bipolar illness, occurring in the first weeks after birth; and mild to moderate depression, occurring weeks to months after birth. Studies have been done focused on postpartum psychosis using a retrospective investigation, which gave only a limited material on the prevalence of psychological disorders in postpartum women. The investigators hypothesized that different pathways to psychosis function as the risk factors which may be overlapped, truly independent, mediating, or moderating, in new mothers who are at high risk and/or during the early period of delivery. In addition, the investigators purposed that the temporal sequence of biological, social and demographic variables are also the potential factors contributing to the development of postpartum psychosis.

Interventions

None listed

Sponsors

Nanjing Medical University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

* Pregnant women * Chinese

Exclusion criteria

* Age \< 18 years or \> 50 years * Gestational age \< 32 weeks

Design outcomes

Primary

MeasureTime frame
Incidence of psychoses3 months and 6 months postpartum

Secondary

MeasureTime frame
Antepartum social statusOne year before labor and delivery (recorded by antepartum communication)
Antepartum psychological level1 day before birth
Intrapartum complications1 day after birth
Baby characteristicsOne minute, 5min, 15min after baby was born
Antepartum economic levelOne year before labor and delivery (recorded by antepartum communication)
Medical caregiver characteristicsOne day before and after the labor completion
Parturient family characteristicsOne week before labor and delivery, recorded by investigators through patients' antepartum communication
Intrapartum medical proceduresOne day after birth
Maternal characteristicsOne day after birth

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026