Obesity, Overweight
Conditions
Brief summary
This purpose of this study was to test the use of chewing gum as an adjunct to lifestyle modification to facilitate appetite control and weight loss in overweight and obese individuals.
Interventions
BEHAVIORALLifestyle modification
16 weekly followed by 8 monthly group behavioral weight loss sessions.
BEHAVIORALLifestyle modification plus gum
16 weekly followed by 8 monthly group behavioral weight loss sessions. Subjects were also given gum along with instructions for times and occasions to chew with the aim of facilitating weight loss and appetite control.
Sponsors
St. Luke's-Roosevelt Hospital Center
University of Pennsylvania
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* 21-75 years of age * Body Mass Index of 25-45 inclusive
Exclusion criteria
* major medical psychiatric conditions * medications know to effect weight * full or partial dentures * 18 or fewer teeth * regular gum chewing (≥ 2 pieces/day) * use of any tobacco product * sensitivity to the following ingredients (mint, magnolia bark, eggs, or English Muffins) * history of PKU * sensitivity or allergy to aspartame * current/history of alcohol abuse or addiction (within 5 year) * recreational drug use * recent significant weight change (+/- 5% in previous 6 months) * currently pregnant or nursing and willingness not to get pregnant during course of study * participation in any other research studies * proximity to clinic (within one hour) * access to reliable transportation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight loss | Week 16 and 52 |
Secondary
| Measure | Time frame |
|---|---|
| Appetite control | Weeks 4, 8, 12, 16 and 52 |
Countries
United States
Outcome results
None listed