Anatomic and Visual Function Assessments on Asymptomatic HIV-positive Patients

Anatomic and Visual Function Assessments on Asymptomatic HIV-positive Patients Using Optical Coherence Tomography and Frequency Doubling Technology Perimetry

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00871078

Enrollment

Registered

2009-03-30

Start date

2008-06-30

Completion date

2009-09-30

Last updated

2009-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acquired Immunodeficiency Syndrome, HIV Infections

Brief summary

The purpose of this study is to assess retinal nerve fiber layer thickness and macular thickness measured with optical coherence tomography (OCT) on patients infected by HIV virus without ocular manifestations and to correlate these results with perimetric findings assessed by frequency doubling technology perimetry (FDT).

Interventions

DEVICEOptical Coherence Tomography (OCT)

Macular and retinal nerve fiber layer OCT (Stratus OCT, Carl Zeiss Meditec, Dublin, CA) will be performed both in patients and controls

DEVICEFrequency Doubling Technology (FDT) perimeter

24-2 FDT Threshold (Humphrey Matrix, Carl Zeiss Meditec, Dublin CA; Welch-Allyn, Skaneateles, NY) will be performed both in patients and controls.

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Clinical diagnosis of AIDS * Best-corrected visual acuity 20/25 or better * Refractive error of 0±5.0 diopters and astigmatism of 0±3.0 diopters * Normal intraocular pressure (≤21mmHg)

Exclusion criteria

* Cataract or any visible media opacity * HIV-related infectious retinopathy * Risk factors for the development of glaucoma

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026