Obesity
Conditions
Keywords
Obesity, wholegrain, wheat, cardiovascular disease
Brief summary
The aim of this study is to investigate the potential beneficial effect of wholegrain on body weight and composition as well as cardiovascular risk in overweight women.
Detailed description
Objective: To study the effect of the 'wholegrain concept', i.e. high intake of wheat wholegrain (WW) vs. refined wheat (RW) grain products on body weight and composition. Design: In this open-labeled randomized trial, 72 postmenopausal women with metabolic syndrome features were prescribed a mild calorie-restricted diet with a deficit of \ 1,250kJ/d. Following 2 weeks run-in period on RW products, they were randomized to 12 weeks intervention with RW or WW products providing 2,000kJ/d.
Interventions
OTHERwholegrain
wholegrain wheat vs. refined wheat products
OTHERrefined wheat
refined wheat products
Sponsors
BARILLA G. e R. Fratelli S.p.A., Parma, Italy
European Commission
University of Copenhagen
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
40 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI 27-37 * Postmenopausal (\>1y) women * 40-70 years old
Exclusion criteria
* Medication (hypertensive treatment not included) * BP \> 160/100 * Fasting glucose \> 7mM * Fasting cholesterol \> 6.5mM * Smoking * Known chronic illnesses
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body weight and composition | 0, 6 and 12 wks |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular risk markers | 0, 6 and 12 wks |
| Fecal parameters | 0 and 12 wks |
Countries
Denmark
Outcome results
None listed