Obesity
Conditions
Keywords
weight reduction, low-carbohydrate, body fat, telemedicine, cardiovascular risk markers
Brief summary
The burden of overweight and obesity has dramatically increased during the last decades. High carbohydrate intake, particularly refined carbohydrates, probably increase the risk of obesity, type 2 diabetes, and metabolic syndrome. There is evidence that energy-restricted low-carbohydrate diets show greater weight loss and better improvement of cardiovascular risk markers compared to energy-restricted low-fat diets. Beside macronutrient relations, efficacy of weight loss programs depends on care and control. The investigators aim to investigate whether or not a carbohydrate-restricted telemedically guided weight loss program results in a more pronounced weight loss and influences metabolic risk markers more beneficial than a fat-restricted diet.
Detailed description
see brief summary.
Interventions
OTHERenergy-restricted, CHO-restricted diet
carbohydrate content of the diet \< 40% Frequency: daily Duration: 12 months
OTHERenergy-restricted, CHO-rich diet
carbohydrate content of diet \> 55% Frequency: daily Duration: 12 months
Sponsors
Heart and Diabetes Center North-Rhine Westfalia
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* age 18-70 years * body mass index \> 27 kg/m2
Exclusion criteria
* history of cardiovascular symptomatology * cholelithiasis * urolithiasis * insulin dependent diabetes * pacemaker implantation * pregnancy * lactation * vegetarianism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| body weight | 12 months |
Secondary
| Measure | Time frame |
|---|---|
| waist circumference | 12 months |
| blood pressure | 12 months |
| blood lipids | 12 months |
| parameters of glucose metabolism | 12 months |
| fat mass | baseline, 12 months |
Countries
Germany
Outcome results
None listed