Magnetic Resonance Imaging (MRI) Study of the Hippocampus After Infarction in the Territory of the Middle Cerebral Artery

To Observe Delayed Neuronal Death of Hippocampus After Middle Cerebral Artery Infarction Through Magnetic Resonance Imaging(MRI) Volume Measurement and Magnetic Resonance Spectroscopy(MRS) Study of Hippocampus

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00867581

Enrollment

Registered

2009-03-24

Start date

2008-09-30

Completion date

Unknown

Last updated

2009-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Stroke

Keywords

middle cerebral artery, infarction, chronic stage, hippocampal volume, MRI, MRS, neuropsychologic assessment

Brief summary

The purpose of this study is to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.

Detailed description

40 patients with middle cerebral artery infarction and 40 healthy volunteers will be observed. All of them will receive MRI scan and the assessment of the neuropsychological function (MMSE, AVLT, HAMD) intending to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Clinical diagnosis of middle cerebral artery infarction * At least six months from the stroke * Must be able to measure his(her) neuropsychologic function (by MMSE, AVLT)

Exclusion criteria

* Unable to undergo examinations due to disturbances of consciousness or medical conditions * Severe dementia, apraxia, disturbances of sensation or perception * Serious complications including severe heart failure, hepatic dysfunction, renal insufficiency,or shock * Parkinson's disease, malignant tumor, autoimmune diseases

Countries

China

Contacts

Primary ContactWei Wang, Doctor

wwang_tjh@126.com86-027-8366-3648

Outcome results