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Biopsy Incisional With Trepan in Periocular Lesions

Biopsy Incisional With Trepan in Periocular Lesions

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00865813
Enrollment
40
Registered
2009-03-19
Start date
2008-12-31
Completion date
2009-12-31
Last updated
2009-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tumor

Keywords

Punch biopsy,, periocular, tumors.

Brief summary

The purpose of this study was to identify accuracy rates of 2mm punch biopsy technique in diagnosing periocular malignancy.

Detailed description

In each case, the histology obtained at biopsy was compared with that identified at the time of tumor excision.

Interventions

PROCEDUREPunch Biopsy

1. Instillation of anesthetic eye drops. 2. Asepsis 3. Placement of surgical cloths and drapes 4. Infiltration of the involved region with anesthetic solution plus adrenalin in1:200.00 dilution. 5. Trephination of the most typical area of the lesion with a punch (2mm in diameter) of stainless steel by applying gentle pressure and twisting the trephine until its introduction into the suspicious lesions 6. Removal of the excised tissue with the aid of an insulin needle or conjuntival forceps, the base then bein cut with an number 11 surgical blade

Sponsors

University of Sao Paulo
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* All lesions were initially examined at the slitlamp, after which lesions with malignant characteristics such as texture, size or color alterations asociated with ulceration, prominent borders or elevated contours, irregular borders, telangiectasias or loss of eyelashes were included.

Exclusion criteria

* Lesions with not malignant characteristics

Design outcomes

Primary

MeasureTime frame
accuracy, positive predictive value, negative predictive value, sensitivity, specificityIn each case, the histology obtained at biopsy was compared with that identified at the time of tumor excision.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026