AIDS, Dementia
Conditions
Brief summary
Patients will be followed every 6 months for a total of 5 visits (Month 0, 6, 12, 18 and 24). The first visit is the screening and entry visit which can occur at any time after the subject finishes SEARCH 001 study but preferably it should occur approximately 6 months after SEARCH 001 study completion. At each visit, patients will undergo the following 1. Assessment of function including activity of daily living questionnaire 2. History of medical illnesses, medication history 3. Neurological examination: All patients will have a neurological evaluation and neuropsychological evaluation to characterize neurocognitive and neurological status. (It is possible that patients within the non-dementia group will meet criteria for dementia after close testing is completed). 4. Neuropsychological assessment: 5. Thai Depression Inventory. 6. HIV viral load and storage of blood for proviral DNA level Final outcome assessment based on all available data. If possible, it is intended that these diagnoses will be determined through monthly VTC conference calls with UH investigators. This consensus conference will include the Thai investigators, the UH neurologist, the UH neuropsychologist and the UH principal investigators.
Interventions
None listed
Sponsors
Thai Red Cross AIDS Research Centre
SEARCH Research Foundation
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* All patients who have completed the SEARCH 001 study are eligible to enroll in this SEARCH 001.1 study provided that they understand and voluntarily sign the informed consent form.
Exclusion criteria
* None
Countries
Thailand
Outcome results
None listed