Acute Effects of Dietary Proteins on Postprandial Lipemia, Incretin Responses and Subclinical Inflammation in Obese Subjects

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00863564

Enrollment

Registered

2009-03-18

Start date

2009-03-31

Completion date

2009-10-31

Last updated

2009-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Postprandial Lipemia, Atherosclerosis, Inflammation, Postprandial Incretins

Keywords

Postprandial Period, Postprandial Lipaemia, Incretins, Subclinical Inflammation, Obesity, Atherosclerosis, Triglyceride, Lipoproteins, Postprandial inflammation

Brief summary

The purpose of this study is to determine the effects of dietary protein on blood lipids and gut hormones after a fat-rich meal. Hypothesis: Certain dietary proteins reduce the amount of fat circulating in the blood stream following a fat rich meal. The effect is dependant of both the quality and the quantity of protein ingested.

Interventions

DIETARY_SUPPLEMENTCaseine

DIETARY_SUPPLEMENTCod

DIETARY_SUPPLEMENTGluten

DIETARY_SUPPLEMENTWhey Isolate

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

40 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* BMI \> 30 kg/m2 & \< 45 kg/m2

Exclusion criteria

* Diabetes * Lipid lowering drugs * Liver-, Kidney- and/or Heart Disease * Serious Hypertension (160/110)

Design outcomes

Primary

Measure	Time frame
Triglyceride	0h- 2h- 4h- 6h- 8h postprandial

Secondary

Measure	Time frame
Inflammatory markers	0h- 1h- 2h- 4h- 6h- 8h postprandial
Incretins	0h -1h -2h -4h -6h -8h Postprandial

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 28, 2026