Influence of Protein Source on Satiety and Metabolism

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00862329

Enrollment

120

Registered

2009-03-16

Start date

2008-03-31

Completion date

2010-11-30

Last updated

2012-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Healthy subjects

Brief summary

Dietary protein is the more satiating nutrient, however it is not clear whether satiety may be influenced by the nature of the protein. This study was designed to assess potential differences between protein sources on satiety and their relationship with digestive and metabolic kinetics.

Interventions

DIETARY_SUPPLEMENTCasein-enriched diet

Subjects consume for 9 days a supplement of 30g/d of casein

DIETARY_SUPPLEMENTMilk soluble protein-enriched diet

Subjects consume for 9 days a supplement of 30g/d of milk soluble protein

DIETARY_SUPPLEMENTCasein and milk soluble proteins-enriched diet

Subjects consume for 9 days a supplement of 30g/d of a mix of casein and milk soluble protein

DIETARY_SUPPLEMENTSoy proteins-enriched diet

Subjects consume for 9 days a supplement of 30g/d of soy protein

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* BMI between 25 and 30

Exclusion criteria

* allergy to milk proteins

Design outcomes

Primary

Measure	Time frame
satiety	7 days

Secondary

Measure	Time frame
hormonal profiles, digestive fluxes of nutrients, postprandial dietary N metabolism	9 days

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 23, 2026