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Case Volume and Adenoma Rate During Screening Colonoscopy

Case Volume and Adenoma Detection Rates During Screening Colonoscopy

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00860665
Enrollment
12134
Registered
2009-03-12
Start date
2006-10-31
Completion date
2009-03-31
Last updated
2009-03-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer

Keywords

colorectal cancer, prevention, colonoscopy, screening, quality assessment, colorectal cancer prevention

Brief summary

Screening colonoscopy has been established as the most effective means of colorectal cancer prevention. This is based on the fact that colonoscopy detects and removes colonic polyps (adenomas) which are known to progress to cancer if left untreated. The present study examines the question whether case volume (i.e., the number of colonoscopies performed per year) correlates with colonoscopy quality, i.e., adenoma detection rate.

Detailed description

21 private practice gastroenterologist endoscopists from Berlin performed a prospective quality assessment study including at least 10.000 screening colonoscopies. After informed consent, patients data are included (age, sex, family history, colonoscopy performance parameters and findings, therapy performed, histology of biopsies and/or polypectomies, complications (immediate and late) and patient acceptance. The latter was retrieved by patient questionnaires returned after a minimum of 2 weeks. Data were centrally collected in an anonymized way Primary outcome parameter: * Correlation of adenoma detection rate with case volume and other confounding factors (e.g., withdrawal time) Secondary outcome parameters: * Complications and method of assessment (immediate recording versus later questionnaire enquiry) * Quality of bowel preparation in relation to outcome Patient acceptance in relation to procedural factors (e.g., sedation) * Quality of pathology reports and histologic outcome of polypectomy Later follow-up (after 5-10 years) of the preventive effect of colonoscopy is planned and has been part of the protocol and patient consent form.

Interventions

None listed

Sponsors

Interest group of Berlin private practice gastroenterologists
CollaboratorUNKNOWN
Charite University, Berlin, Germany
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
55 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

* all persons willing and able to undergo screening colonoscopy over the age of 55 years

Exclusion criteria

* any condition not compatible with the definition of screening colonoscopy

Design outcomes

Primary

MeasureTime frame
Correlation of adenoma detection rate with case volume of endoscopists18 months

Secondary

MeasureTime frame
Patient acceptance in relation to procedural factors (e.g. sedation)18 months

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 26, 2026