Dysphagia, Peristomal Wound Infection
Conditions
Keywords
Percutaneous endoscopic gastrostomy, peristomal wound infection, antibiotic mouth wash solution, prophylaxis prior Percutaneous endoscopic gastrostomy (PEG)
Brief summary
Percutaneous endoscopic gastrostomy (PEG) is commonly used for long term enteral feeding of patients with severe dysphagia. The most common complication is peristomal wound infection. The possible mechanism the bacterial from the oral cavity disseminate during the PEG insertion through the stomach to the abdominal wall, in spite the routine use of antibiotic prophylaxis, have reported low rates of wound infection in patients who were already receiving antibiotics at the time of PEG Our hypothesis that washing the oral cavity with antibiotic solution prior the insertion PEG , We planned a prospective, randomised, double blind, one centre study of antibiotic mouth wash solution (0.2% Chlorhexidine gluconate) as.prophylaxis in PEG
Interventions
DRUGChlorhexidine gluconate 0.2%
Mouth wash prior to procedure
OTHERPlain water
Mouth wash prior to procedure
Sponsors
Hillel Yaffe Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
45 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* All patients scheduled to undergo PEG
Exclusion criteria
* Previous GI surgery * Coagulopathy * Sepsis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assess impact mouth wash (containing 0.2% Chlorhexidine gluconate) (Taro Pharmaceutical Industries Haifa Israel) prior PEG insertion. | One month |
Secondary
| Measure | Time frame |
|---|---|
| Follow the peristomal wound infection in patients who had prepared by mouth wash to a group a patients without mouth washing. | One month |
Outcome results
None listed