Nerve Morphology in Diabetic Patients

Posterior Interosseous Nerve Pathology May Provide Novel Insights Into Both Predisposition and Potential Vascular Basis for the Development of Carpal Tunnel Syndrome in Diabetic Patients.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00856011

Enrollment

Registered

2009-03-05

Start date

2003-12-31

Completion date

2008-04-30

Last updated

2009-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal Tunnel Syndrome, Diabetes Complications, Entrapment Neuropathies, Peripheral Neuropathy

Brief summary

The underlying basis of carpal tunnel syndrome and the basis of its increased incidence in diabetes are unknown. The aim of this study was to quantified pathology in an uncompressed nerve (posterior interosseous nerve in the forearm between diabetic and non-diabetic patients with CTS.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Diagnosis of carpal tunnel syndrome based in clinical history and symptoms * Confirmed by nerve conduction studies

Exclusion criteria

* Other focal nerve entrapments * Cervical radiculopathy * Inflammatory joint disease * Renal failure * Thyroid disorders * Previous wrist fracture * Long-term exposure to vibrating tools * Age under 18

Design outcomes

Primary

Measure	Time frame
Nerve morphology (Fascicular area, myelinated nerve fiber density, endoneurial capillary density and subperineurial space	—

Countries

Sweden

Outcome results