Depression, Epilepsy, Healthy
Conditions
Keywords
Epilepsy, Depression, Neurology, fMRI, Healthy Controls
Brief summary
The goal of this study is to determine whether there are unique markers on neuroimaging that are associated with depression in epilepsy.
Detailed description
Symptoms of depression is commonly seen in patients with epilepsy. There are similarities and differences between depressive symptoms in epilepsy when compared with primary depression. Through the use of fMRI (Functional MRI), we hope to determine whether there are unique markers on neuroimaging that are associated with depression in epilepsy.
Interventions
OTHERfMRI
Subjects will undergo MRI scanning to gather data about cognetive functions.
Investigator will evalute the subject during a one on one interview for depression using the Hamilton Depression Rating Scale.
OTHERBeck's Depressive Inventory
Subjects will complete self assessment to evaluate their level of depression.
OTHERInterictal Dysphoric Disorder Inventory (IDDI)
Subject will complete self assessment to determine if there have been any changes in mood, emotions and or feelings from time to time.
Sponsors
Northwell Health
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
For Control Group Inclusion Criteria: * Healthy adults of 18 years of age or older.
Exclusion criteria
* Subject has no history of affective disorders * Subject scores higher than 5 on Hamilton Depression Rating Scale * Subject with prior primary diagnosis of any psychotic disorder, bipolar disorder, anxiety disorder, or any other serious medical or neurological disorder * Subject is pregnant * Subject is unable to undergo a MRI Epilepsy Only Group Inclusion Criteria: * Subject is at least 18 years of age * Subject has confirmed temporal lobe epilepsy (TLE)
Countries
United States
Outcome results
None listed