Study Examining the Effect of Exercise in People With Rheumatoid Arthritis Taking Anti-TNFalpha Medication

Randomized Controlled Trial Examining The Effect Of Exercise In People With Rheumatoid Arthritis Taking Anti-TNFalpha Medication

Status

UNKNOWN

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00855322

Enrollment

Registered

2009-03-04

Start date

2008-01-31

Completion date

2009-07-31

Last updated

2009-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arthritis, Rheumatoid

Keywords

Arthritis, Rheumatoid, Exercise, Biological Therapy

Brief summary

The purpose of this study is to determine whether exercise is beneficial for people with rheumatoid arthritis(RA) taking antiTNFalpha medication

Detailed description

Substantial progress has been made in the medical management of RA over the past decade but at present no drug therapy leads to long-term remission for all patients with RA. People may still continue to experience physical, psychological and functional consequences which could benefit from rehabilitation.little research exists on the effects of exercise for people with RA taking anti-TNFalpha therapy medication. It is proposed to conduct a randomized controlled trial to examine the effects of group exercise therapy in a gym setting or in a hydrotherapy pool compared to a control group.

Interventions

OTHERGym exercise group intervention

Gym based circuit class

OTHERHydrotherapy group exercise intervention

Hydrotherapy group exercise class

OTHERControl group

No intervention

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Patients with RA receiving anti-TNFalpha therapy medication for more than three months * Consenting male and female patients aged 18 - 70 years * Patients will have a documented diagnosis of RA as classified by the American College of Rheumatology (ACR) criteria * ACR functional class I, II, III

Exclusion criteria

* Patients who have attended physiotherapy in the past three months * Patients to whom exercise therapy or hydrotherapy are contraindicated * Patients who have undergone joint surgery in the past six months

Design outcomes

Primary

Measure	Time frame
Stanford Health Assessment Questionnaire	Baseline, 8 weeks and 24 weeks

Secondary

Measure	Time frame
50 foot Walk Test	Baseline, 8 weeks and 24 weeks

Countries

Ireland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 29, 2026