Follow-up Study of Small-intestinal Mucosal Injuries in Chronic Non-steroidal Anti-inflammatory Drugs (NSAIDs)-Users

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00854490

Enrollment

100

Registered

2009-03-03

Start date

2009-10-31

Completion date

Unknown

Last updated

2009-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enteropathy

Brief summary

The purpose of this study is to evaluate the long-term clinical significance of small-intestinal mucosal injuries in chronic NSAIDs-users.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Inclusion criteria

* written informed consent * 20 to 85 years of age * RA, OA, or low back pain * taking oral diclofenac sodium over 3 months * No change of drugs before 3 months * under 5 mg of corticosteroid use * CRP \< 1mg/dl

Exclusion criteria

* known or suspected small-bowel disease, including Crohn's disease and seronegative arthritis * prostaglandins, metronidazole or salazosulfapyridine * can not swallow * with pacemaker * after gastrointestinal operation * serious concomitant cardiovascular, endocrine, gastrointestinal(including symptoms of ileus), neurologic, psychiatric, renal, or respiratory disease. * any other conditions that the investigator feels would interfere with data interpretation or create under risk

Countries

Japan

Contacts

Primary ContactNaoki Ohmiya, MD., Ph.D.

nohmiya@med.nagoya-u.ac.jp81-52-744-2172

Outcome results