Cardiac Output
Conditions
Keywords
Comparison of CO by new method to clinician's estimate and implied CO from the measurement of arteriovenous oxygen content difference.
Brief summary
The ability to measure cardiac output (CO) accurately and reproducibly at frequent intervals remains elusive to the clinician caring for critically ill pediatric patients even though a large proportion of these children are known to have hemodynamic compromise as a result of their illness. Current techniques used in adults to measure CO are not suitable for routine use with pediatric patients. A new ultrasound dilution approach provides an opportunity to measure cardiac output and blood volumes in pediatric patients. The main aim of this study is to compare CO measured by the new method with the clinician's estimate and implied CO from the measurement of the arteriovenous oxygen content difference.
Interventions
None listed
Sponsors
National Heart, Lung, and Blood Institute (NHLBI)
Transonic Systems Inc.
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 16 Years
Healthy volunteers
No
Inclusion criteria
* Patients with in situ central venous and arterial catheters * Ability to draw blood from arterial and central venous catheters * Presence of parent or guardian to provide consent
Exclusion criteria
* Patients over 16 years of age.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare CO measured by the new method with clinician's estimate and implied CO from measurement of arteriovenous oxygen content difference. | 5-8 minutes minimum |
Secondary
| Measure | Time frame |
|---|---|
| Measure blood volumes to compare effects of volume infusion and furosemide. | 5-8 minutes minimum |
Countries
United States
Outcome results
None listed