Malaria
Conditions
Keywords
Forest malaria prevention, Long-lasting insecticidal hammocks, Cluster randomized trial, Central Vietnam
Brief summary
In Central Vietnam, forest malaria remains difficult to control due to the complex interactions between human, vector and environmental factors. Untreated bednets had a significantly protecting effect for villagers, except for those regularly sleeping in the forest, who suffer a significantly higher number of clinical attacks. Thus, there is need to target this high-risk group with new intervention based on long-lasting insecticidal materials. Hammocks are extensively used by people working in the forest, therefore long-lasting insecticidal hammocks (LLIH) could achieve a good individual protection. The Investigators proposed to evaluate their effectiveness in a community-based trial, comparing them to the standard vector control methods (insecticide-treated nets).
Detailed description
In Central Vietnam, forest malaria remains difficult to control due to the complex interactions between human, vector and environmental factors. A community-based study carried out between 1999 and 2001 showed that regular forest activity was a strong risk factor for malaria infection. Untreated bednets had a significantly protecting effect for villagers, except for those regularly sleeping in the forest, who suffered a significantly higher number of clinical attacks. Thus, there is need to target this high-risk group with new intervention based on long-lasting insecticidal materials. Hammocks are extensively used by people working in the forest, therefore long-lasting insecticidal hammocks (LLIH) could achieve a good individual protection. The Investigators proposed to evaluate their effectiveness in a community-based trial, comparing them to the standard vector control methods (insecticide-treated nets): communities have been grouped into clusters of about 1000 înhabitants, and clusters were randomized to either the active intervention or the active control, and followed up for 24 month.
Interventions
Locally-made hammocks covered with long lasting insecticidal nel (LLIN)
Insectice-treated net
Sponsors
Study design
Eligibility
Inclusion criteria
* All residents in the 20 concerned study clusters and willing to give informed consent to participate
Exclusion criteria
* People not willing to give informed consent to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of malaria prevalence and incidence | 24 months |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of malaria sero-prevalence | 24 months |
Countries
Vietnam