Effects of Arabinoxylan-Oligosaccharides Compared to Other Prebiotics in Healthy Subjects

Effects of Arabinoxylan-Oligosaccharides on Colonic Metabolism and Microbial Composition Compared to Other Prebiotics in Healthy Subjects

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00853034

Enrollment

Registered

2009-02-27

Start date

2006-10-31

Completion date

2007-09-30

Last updated

2009-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

gastrointestinal effects, prebiotic

Brief summary

The purpose of the study is to evaluate the effects of arabinoxylan-oligosaccharides (AXOS) on the colonic metabolism and microbial composition, and to compare these effects with the reference prebiotic fructo-oligosaccharide enriched inulin.

Interventions

DIETARY_SUPPLEMENTFOS-IN

prebiotic fructo-oligosaccharide enriched inulin intake period: 2 weeks, 1.25 or 2.50g every morning and evening

DIETARY_SUPPLEMENTAXOS

arabinoxylan-oligosaccharides (AXOS) intake period: 2 weeks, 1.25 or 2.50g every morning and evening

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy * 18-45 years * regular eating pattern

Exclusion criteria

* gastrointestinal complaints * antibiotic intake * medication influencing gut transit or microbiota * abdominal surgery * pregnancy

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026