Tolerance and Prebiotic Activity of Arabinoxylan-Oligosaccharides in Healthy Subjects

Tolerance and Prebiotic Activity of Arabinoxylan-Oligosaccharides in Healthy Subjects: a Randomized, Placebo-Controlled Cross-Over Study

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00852813

Enrollment

Registered

2009-02-27

Start date

2007-10-31

Completion date

2008-06-30

Last updated

2009-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

tolerance, prebiotic, gastrointestinal effects

Brief summary

The purpose of the study is to evaluate the tolerance of a higher dose of arabinoxylan-oligosaccharides (AXOS) and their prebiotic activity in healthy subjects.

Interventions

DIETARY_SUPPLEMENTarabinoxylan-oligosaccharides (AXOS)

intake period: 3 weeks, 10 g/day

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy * 18-45 years * regular eating pattern

Exclusion criteria

* gastrointestinal complaints * antibiotic intake * medication influencing gut transit or microbiota * abdominal surgery * pregnancy

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026