FindTrial
Sign In

Impact of N-Acetylcysteine on Oxidative Stress and Renal Function in Deceased Kidney Transplant Recipients

Oxidative Stress and Postoperatory Renal Function in Deceased Kidney Transplantation

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00851708
Enrollment
Unknown
Registered
2009-02-26
Start date
Unknown
Completion date
Unknown
Last updated
2009-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deceased Kidney Transplantation

Keywords

kidney, deceased kidney transplant, oxidative stress, renal function measurements

Brief summary

The aim of this interventional, prospective, randomized clinical trial is to evaluate the impact of the antioxidant N-acetylcysteine on oxidative stress in the first seven postoperative days and on renal function in the first three postoperative months in deceased kidney transplantation.

Interventions

DRUGN-acetylcysteine

600 mg bid orally from day 1 to 7 postoperative

Sponsors

Fundação de Amparo à Pesquisa do Estado de São Paulo
CollaboratorOTHER_GOV
University of Sao Paulo
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* First transplant * Deceased kidney transplant

Exclusion criteria

* postoperative recovery at critical care unit * illicit drug addiction * psychiatric disorders

Design outcomes

Primary

MeasureTime frame
Tiobarbituric acid reactive species measuresFirst seven postoperative days

Secondary

MeasureTime frame
Serum creatinine7, 15, 30, 60, 90 postoperative day

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026