Comparison of Anwar and Melles Techniques in Deep Anterior Lamellar Keratoplasty (DALK) for Keratoconus Patients

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00850148

Enrollment

Unknown

Registered

2009-02-24

Start date

2008-05-31

Completion date

2009-09-30

Last updated

2012-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Keratoconus

Keywords

Anwar, Melles, Keratoconus

Brief summary

This study will be performed on patients who come to labbafinejad ophthalmic clinic from 20 March 2008. Keratoconus diagnosis will be determined by clinical finding in slit lamp, keratometery and topographic characteristics. Patients will be randomly placed in group A and B. In group A, Anwar surgical method and in B, Melles surgical method, will be done. This is not a blind study due to surgeons' knowledge. All patients will receive Btamethazone drop and Chloramphenicol every 6 hours and will be tapered in two months. In the end anatomical results, complications, BCVA, UCVA, astigmatism, endothelial cell numbers will be compared in two groups by using specular microscopy. Contrast sensivity, central corneal diameter, interface wrinkling and opacity will be measured by metrovison, Confoscan, Photoslit in months 3, 6, 12, respectively and will be evaluated afterwards.

Interventions

PROCEDUREAnwar

Anwar surgical method

PROCEDUREMelles

Melles surgical method

Eligibility

Sex/Gender

ALL

Age

15 Years to 45 Years

Healthy volunteers

Inclusion criteria

* patients with keratoconus * 15\<age\<45 * contact lens intolerance

Exclusion criteria

* Having a history of any other ophthalmic or systemic problem * Central corneal scar * descemet's membrane detachment

Countries

Iran

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026