Gene Polymorphisms and Gene Products as Biological Markers of Aging and Correlation With Clinical Geriatric Assessment, Tolerance of Chemotherapy and Outcome in Elderly Breast Cancer Patients

Gene Polymorphisms and Gene Products as Biological Markers of Aging and Correlation With Clinical Geriatric Assessment, Tolerance of Chemotherapy and Outcome in Elderly Breast Cancer Patients.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00849758

Acronym

EBS

Enrollment

110

Registered

2009-02-24

Start date

2009-05-31

Completion date

2014-09-30

Last updated

2014-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer, Elderly

Keywords

breast cancer, elderly, biomarker

Brief summary

The goal is to study the biology of aging in breast cancer patients, and to study the impact of chemotherapy on aging related blood biomarkers.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

70 Years to No maximum

Healthy volunteers

Inclusion criteria

* 70 years or older * Female * Early breast cancer * Candidate for systemic adjuvant therapy

Design outcomes

Primary

Measure	Time frame
the primary question is whether Chemotherapy affects biological aging markers, such as telomere length and immune status	2 years

Countries

Belgium

Outcome results