Dengue
Conditions
Brief summary
The objective of this study was to evaluate the effect of chloroquine in the treatment of patients with dengue.
Interventions
DRUGPlacebo
Placebo bid for three days
DRUGChloroquine
Chloroquine bid for three days
Sponsors
Fundação de Amparo à Pesquisa do Estado de São Paulo
University of Sao Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients suspected of having dengue disease * Patients were included in the study if they presented with fever and at least two other symptoms, such as: * headache * pain behind the eyes * muscle and bone or joint pains * nausea * vomiting * rash associated to dengue for less than 72 hours
Exclusion criteria
* Pregnant * Younger than 18-years old * Either cardiac or neurologic disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of the disease | one week |
Secondary
| Measure | Time frame |
|---|---|
| Intensity and days of fever and symptoms | one week |
Countries
Brazil
Outcome results
None listed