Mapping Mood in the Subthalamic Nucleus in Parkinson's Disease (PD)

Mapping Mood in the Subthalamic Nucleus in PD

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00847431

Acronym

MOOD-D

Enrollment

Registered

2009-02-19

Start date

2008-12-31

Completion date

2015-12-31

Last updated

2016-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, Depression, Parkinson's Disease

Keywords

Subthalamic Nucleus, Deep Brain Stimulation, Depression, Anxiety, Parkinson's Disease

Brief summary

The goal of this study is to determine the vulnerability of mood-related neurocircuitry in Parkinson Disease (PD) using deep brain stimulation of the subthalamic nucleus (STN DBS).

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

40 Years to No maximum

Healthy volunteers

Inclusion criteria

for STN-DBS subjects: * Age 40 or older * DBS STN Surgery in past 2 to 36 months * Ability to tolerate turning off Stimulators * Ability to read and comprehend questions * English speaking

Exclusion criteria

for STN-DBS subjects: * Other severe complications post surgery: stroke, seizure, major loss of consciousness, other brain trauma/surgery, or head injuries(i.e. near drowning), encephalitis, or hydrocephalus, blindness, deafness * Clinically determined Dementia ( Most recent MMSE score of \>24) Inclusion Criteria for Control subject: * Age 40 or older * Ability to read and comprehend questions * English speaking

Countries

United States

Outcome results