Hypogonadism
Conditions
Keywords
Hypogonadism, Abdominal obesity, Physical exercise, Testosterone
Brief summary
With advancing age testosterone levels decline in men. Low testosterone levels plus certain symptoms are called Late Onset Hypogonadism (LOH). Adipose tissue may contribute to testosterone deficiency. On the other hand testosterone deficiency again leads to a decrease in lean body mass and an increase in fat mass - one of the clinical signs / symptoms of LOH. Lifestyle changes (diet, exercise) alone or in combination with testosterone replacement (TRT), have an influence on the symptoms of LOH. The aim of this study is to assess the additional impact of TRT on Aging Male Symptom Score (AMS) and adiposity (waist circumference) in patients, who are on a diet and exercise program.
Interventions
Male patients \> 35yrs in medical practices fulfilling all criteria for documentation.
Sponsors
Bayer
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
35 Years to 64 Years
Healthy volunteers
No
Inclusion criteria
* Male patients \> 35yrs * Waist Circumference \> 102cm * Clinically and biochemically confirmed hypogonadism (testosterone group) * Willingness to attempt weight optimization
Exclusion criteria
* Androgen dependent carcinoma of the prostate or male mammary gland, past or present history of liver tumours * hypersensitivity towards the active pharmaceutical ingredient or other ingredients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Waist Circumference | At each visit |
Countries
Germany
Outcome results
None listed