Plant Stanol Ester Beverage and Ileostoma Patients

Effects of a Plant Stanolester Beverage on Cholesterol Metabolism Among Human Subjects With Ileostoma

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00846937

Acronym

STOMA

Enrollment

Registered

2009-02-19

Start date

2009-02-28

Completion date

2010-05-31

Last updated

2011-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ileostoma

Keywords

Cholesterol, Plant stanolester, Beverage, Ileostoma, Serum cholesterol level, serum LDL-cholesterol level, Intestinal cholesterol absorption efficiency

Brief summary

We aim to examine efficacy of a plant stanolester beverage to lower serum cholesterol and LDL-cholesterol levels, when given with or without a fatty acid preparation. Study subjects are otherwise healthy proctocolectomized ileostoma patients (n=10), who consume stanolester beverage with or without a fatty acid preparation in a random order for one week period after a standardized low-fat meal. Washout period is 4 weeks. Serum lipids, lipoprotein lipids, sterols and fecal sterols and variables of cholesterol metabolism will be examined accordingly.

Interventions

DIETARY_SUPPLEMENTPlant stanolester and fatty acid

Plant stanol ester 2gr/day and fatty acid in a beverage compared to plant stanol ester 2gr /day and placebo

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy proctocolectomized subjects with an ileostoma

Exclusion criteria

* Chronic illness

Design outcomes

Primary

Measure	Time frame
serum cholesterol level	After treatment perdiods

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026